My ultimate goal is to bridge the gap between the development of the biomedical discoveries and translating them into clinical applications that improve human health. In particular, I am interested in developing and validating computer modeling and simulations in medicine and biology in general.

During my PhD at UNC Chapel Hill, I worked on fluid-structure interaction models of bioprosthetic valves in an in vitro pulse duplicator. The primary software I used for my simulations is IBAMR, which is a distributed-memory parallel implementation of the immersed boundary (IB) method with adaptive mesh refinement (AMR).

During my postdoc at Johns Hopkins University, I worked on modeling gastric biomechanics, drug dissolution, gastroparesis, and gastrointestinal feedback mechanism. For these simulations, I use ViCar3D, which is a Viscous Cartesian grid solver for 3D immersed boundaries based on the sharp-interface immersed boundary method developed by Professor Rajat Mittal.

I currently use OpenFOAM, LIGGGHTS, CFDEM-coupling to do various CFD, DEM, and CFD-DEM simulations of orally inhaled drug products. My current interest includes exploring AI/ML methodologies for data analysis, as well as incorporating them with physics-based modeling approaches to enhance the performance. I am also interested in large language models (especially retrieval-augmented generation and agentic workflow to improve the accuracy and reliability) and other types of in silico modeling approaches for physiological systems.